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Image Search Results
Journal: Blood Neoplasia
Article Title: Microenvironmentally derived fatty acid–binding proteins 4 and 5 are novel therapeutic vulnerabilities in multiple myeloma
doi: 10.1016/j.bneo.2026.100229
Figure Lengend Snippet: DIO exacerbates phenotypic differences between WT and Fabp4/5 dKO mice. Mouse weights over time (A; WT male, n = 9-10; Fabp4/5 dKO male, n = 9-10; WT female, n = 8-10; Fabp4/5 dKO female, n = 10), ultrafocus dual-energy X-ray absorptiometry-Faxitron quantification of total weight (B) and fat weight (C) over the course of HFD administration before tumor cell injection (WT M, n = 9-10; Fabp4/5 dKO M, n = 10; WT F, n = 9-10; Fabp4/5 dKO , n = 10). Glucose levels assessed during glucose (D) and insulin (E) tolerance testing in WT (n = 10) and Fabp4/5 dKO mice (n = 10); statistical analysis performed using 2-way analysis of variance (ANOVA) and Tukey multiple comparisons tests. AUC for glucose tolerance testing (D) and insulin tolerance testing (E); statistical significance was determined using 2-way ANOVA with Tukey multiple comparison tests for panels B-C, whereas unpaired t tests were used for panels D-E (WT, n = 10; Fabp4/5 dKO , n = 10). AUC, area under the curve; min, minute.
Article Snippet: Mouse weights over time (A; WT male, n = 9-10; Fabp4/5 dKO male, n = 9-10; WT female, n = 8-10; Fabp4/5 dKO female, n = 10),
Techniques: Injection, Comparison